The 2026 Picower Lecture with Richard L. Huganir, "Neurotransmitter Receptors: Synaptopathies and Synaptic Engrams"

Building 46, Singleton Auditorium (46-3002), 43 Vassar Street, Cambridge, MA

The 2026 Picower Lecture with Richard L. Huganir, PhD, Johns Hopkins University Speaker: Richard L. Huganir, Ph.D., Bloomberg Distinguished Professor, Department of Neuroscience and Psychological and Brain Sciences; Director, Department of Neuroscience; Kavli Neuroscience Discovery Institute, Johns Hopkins UniversityDate: Wednesday, October 28, 2026Time: 4:00pmLocation: Singleton Auditorium (46-3002, Third Fl of MIT Building 46)Faculty Host: Linlin FanPlease Note: This seminar is offered in person only. Neurotransmitter Receptors: Synaptopathies and Synaptic Engrams Abstract: Neurotransmitter receptors mediate signal transduction at synaptic connections between neurons in the brain. My laboratory has been elucidating the molecular mechanisms that regulate glutamate receptors, the major excitatory neurotransmitter receptors in the central nervous system. We are particularly interested in how glutamate receptor regulation is involved in learning and memory, and other higher brain processes. We have recently focused on AMPA-type glutamate receptors and studied their regulation by posttranslational modifications and by various AMPA receptor-interacting proteins. Regulation of AMPA…

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